Trimethoprim structure activity relationship of drugs

trimethoprim structure activity relationship of drugs

A 4'-OMe group is not essential for high activity, the 4'-Br analog is equiactive and the 4'-Cl analog more active than trimethoprim. Kompis and Wick (80). The derivation of structure activity relationships (SARs) is central to molecular . trimethoprim analogues on Escherichia coli (E. coli) dihy- drofolate reductase. Quantitative Structure-Activity Relationship Studies of a Series of Sulfa Drugs as sulfamethoxazole and the dihydrofolate reductase inhibitor trimethoprim.

trimethoprim structure activity relationship of drugs

Джабба тяжко вздохнул и повернулся к экрану. - Не знаю. Все зависит от того, что ударило в голову автору.

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  • Lecture 7 & 8 Medicinal Chemistry 1 PC 509
  • Trimethoprim