Muscle spasticity in relationship to ms

MS Muscle Spasticity: What It Is, and What to Do About It | Everyday Health

muscle spasticity in relationship to ms

incidence and impact of spasticity in MS muscle spasms.7 However, spasticity does not always .. beneficial effects on MS-related symptoms such as pain. People with MS-related spasticity may occasionally develop a type of muscle spasm, called flexor spasm or extensor spasm, which are reflexes in response to . Multiple sclerosis (MS) is one of the commonest neurological conditions of young Pain and spasticity are two of the commonest symptoms from which people with significant savings in hospitalisation costs in relation to bed-bound patients.

Owing to the paucity and poor quality of evidence identified in this review, no further conclusions regarding the clinical or cost-effectiveness of the remaining interventions for pain or spasticity can be drawn.

muscle spasticity in relationship to ms

Conclusions Many of the interventions identified are not licensed for the alleviation of pain or spasticity in MS. In addition, the lack of evidence relating to their effectiveness may militate against them being used consistently across the NHS. Lastly, the licensing and forthcoming availability of trial evidence relating to the use of cannabinoids in the alleviation of symptoms relating to MS may mean that we are in the ironic position of having better evidence of the effectiveness of new treatments than of any of the currently used drugs.

Recommendations for research The following areas are suggested for further research: Double-blind RCTs, with adequate power and follow-up, of interventions used in current practice for the alleviation of pain and spasticity in MS.

Outcomes should include functional benefit and impact on quality of life.

Spasticity – Causes, Symptoms and Treatments

Development and validation of outcomes measures for pain and spasticity. Treatments for spasticity and pain in multiple sclerosis: Health Technol Assess ;7 Technology assessment reports are completed in a limited time to inform decisions in key areas by bringing together evidence on the use of the technology concerned.

The views expressed in this publication are those of the authors and not necessarily those of the HTA Programme or the Department of Health. The editors wish to emphasise that funding and publication of this research by the NHS should not be taken as implicit support for any recommendations made by the authors.


Criteria for inclusion in the HTA monograph series Reports are published in the HTA monograph series if 1 they have resulted from work commissioned for the HTA Programme, and 2 they are of a sufficiently high scientific quality as assessed by the referees and editors.

The first approach to managing spasticity is to treat the problems that are known to increase risk for developing spasticity.

These include pain of any kind, urinary tract infection and other types of infections, distended bladder or bowel, and pressure sores. A physical therapist can recommend and offer instruction on stretching routines that involve active stretching stretches you do on your own and passive stretching stretches that someone helps you to do.

Medications that may be effective in treating spasticity include Lioresal baclofenZanaflex tizanidineKlonopin clonazepamValium diazepamDantrium dantroleneand Neurontin gabapentin.

Spasticity in MS: What to Expect

The drug most commonly used to treat spasticity, Lioresal baclofencan cause you to feel weak or fatigued. The challenge with Lioresal is finding a dosage that relieves spasticity without causing excessive weakness.

Another treatment option is involves injection of the drug Botox botulinum toxin to block nerve signaling to muscles. In some people whose spasticity is severe and does not respond to oral medication, a pump can be surgically implanted in the abdomen to deliver low doses of baclofen into the spinal canal.

muscle spasticity in relationship to ms

Intrathecal baclofen can be an effective treatment in cases of severe spasticity and the low doses of baclofen utilized limit the side effects of weakness and fatigue. Sign up for emails from MultipleSclerosis.

Stiffness & Spasticity Symptom of MS

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