BACKGROUND: Yacon is a root crop which contains high amounts of The aim of this study was to investigate the effects of yacon syrup on. Yacon roots (Smallanthus sonchifolius) improve oxidative stress in diabetic rats. Instituto Superior de Investigaciones Biológicas (INSIBIO). Carolina Serra-. Instituto Superior de Investigaciones Biológicas (INSIBIO), Another important Andean crop is yacon (Smallanthus sonchifolius) which is a.

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The triglyceride lowering effect could explain at least in part the inhibition of de novo fatty acid synthesis and downregulation of lipogenic enzymes as has been suggested for oligofructose [ 59 ]. The data concerning to the expression of intestinal peptides are shown in Figure 6.

Effect of yacon (Smallanthus sonchifolius) on colonic transit time in healthy volunteers.

American Journal of Clinical Nutrition. Additionally, yacon roots present strong antioxidant activity and anti-inflammatory effects preventing the risks associated with metabolic diseases [ 27 — 29 ]. LA-cp rats fed a high protein fiber diet. Authors contributing to RSC publications journal articles, books or book chapters do not need to formally request permission to reproduce material contained in this article provided that the correct acknowledgement is given with the reproduced material.

If you are the author of this article you still need to obtain permission to reproduce the whole article in a third party publication with the exception of reproduction of the whole article in a thesis or dissertation.

This may take some time to load. Follow us on Twitter or Facebook to stay on top of the latest in scientific research. Hepatic superoxide dismutase and catalase activities were significantly lower in diabetic-treated rats This research was supported by PIP no. Triglycerides and total cholesterol concentrations were determined by enzymatic colorimetric methods using available commercial kits Wiener lab Group, Argentina.


Relationship between serum adiponectin and leptin concentrations and body fat distribution.

No significant changes were observed for the spleen and pancreas in all the studied groups. Robinson belongs to a member yacob Asteraceae family, which ranges through the Andean region in South America [ 1415 ]. Table 3 shows the effects of yacon flour consumption on relative organ weights.

Effect of yacon (Smallanthus sonchifolius) on colonic transit time in healthy volunteers.

Br Med Bull Nutritional strategies represent alternatives to pharmaceutical approaches for reducing hyperglycemia and body weight [ 13 ]. Experiment 1 Investigacioes 12 weeks on HFD or standard chow, the animals were randomly divided into the following groups according to the treatment with or without the addition yacin yacon flour as a dietary supplement for 8 weeks Figure 1.

Additionally, adiponectin and leptin have been implicated in adipose tissue dysfunction [ 6 ].

Moreover, releasing GLP-1 from intestinal L-cells directly into the portal vein could also represent an additional mechanism related to yacon FOS-improved glucose homeostasis [ 55 ]. Supplementary Materials Supplementary Materials Figure S1 provides evidence that yacon supplementation modifies lipid absorption at the intestinal level through an oral triglyceride loading test.

Please enter a personalized message to the dl. Methods Enzyme Anal Andean roots and tubers are underexploited crops; many contain compounds beneficial to health, so a greater knowledge of their properties is important for encouraging their consumption.

Additionally, the presence chlorogenic and caffeic acid in yacon roots could also contribute to the hypolipidemic effect observed after yacon supplement [ 18 ].

The pathogenesis of obesity-associated adipose tissue inflammation; pp. Rats were kept in a breeding room with controlled environment temperature: Home Vol 22 No 1 Hence, yacon roots can be considered a potent and useful functional food. In the second approach, we determined that yacon supplementation potentiates the effects of the Dep reversion to a standard diet.


In this sense, natural products provide a rich source for safe and effective therapeutic compounds with multiple mechanisms of action [ 1213 ]. Inflammation, metaflammation and immunometabolic disorders.

Vol 22 No 1 Support Center Support Center. Annals of the New York Academy of Sciences.

Investigacciones Apr 8. The HFD group received a standard-based diet enriched with eatable lard and carbohydrates modified from [ 33 ] to induce obesity and hyperlipidemia.

Yacon roots (Smallanthus sonchifolius) improve oxidative stress in diabetic rats. | PubFacts

The cellular and molecular bases of leptin and ghrelin resistance in obesity. The authors declare that there are no conflicts of interest. In concordance, increased GLP-1 levels in the investigacionws and in serum were shown when yacon roots were administered to diabetic rats [ 25 ].

Yacon was well tolerated with an excellent side effect profile. For instance, rodents chronically exposed to a high-fat diet develop dyslipidemia, white adipose tissue expansion, insulin resistance, and altered metabolic regulatory hormones [ 3233 ] constituting a useful tool to evaluate the potential mechanisms underlying the investigacipnes of yacon on obesity.

At this time, animals fed HFD reached obesity status Figure 1.

Journal of Obesity

It has been shown that it reduces invewtigaciones glucose production and stimulates glucose uptake and fatty acid oxidation in skeletal muscle [ 51 ]. We can help you send a request to the authors directly. At least 15 nonadjacent microscope fields were analyzed in each tissue.